Latvia is increasing investment to support research and development and seeks to expand research cooperation with the United States. In September 2024 Latvia and the United States signed an updated Science and Technology Agreement, which provides a framework for increased cooperation.  While Latvia hosts a robust research ecosystem, researchers have been less effective in commercializing their products.  With new amendments to the Law on Scientific Activity supporting technology transfer activities, stakeholders are eager to develop improved commercialization models. An Open World program focused on research commercialization would provide opportunities to develop new transatlantic relationships between institutions and researchers, as well as share best practices from U.S. institutions that expand public/private sector cooperation in Research and development. By building U.S. connections and offering workable models for commercialization, the program will offer innovators options grounded in transatlantic relationships and values as an alternative to cooperation with malign actors.